EC Number | Cloned (Comment) | Organism |
---|---|---|
2.1.1.254 | expression in Escherichia coli | Saccharopolyspora erythraea |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.254 | S-adenosyl-L-methionine + erythromycin C | Saccharopolyspora erythraea | - |
S-adenosyl-L-homocysteine + erythromycin A | - |
? | |
2.1.1.254 | S-adenosyl-L-methionine + erythromycin D | Saccharopolyspora erythraea | - |
S-adenosyl-L-homocysteine + erythromycin B | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.254 | Saccharopolyspora erythraea | A4F7P5 | - |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.1.1.254 | S-adenosyl-L-methionine + erythromycin C = S-adenosyl-L-homocysteine + erythromycin A | (1) | Saccharopolyspora erythraea |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.254 | S-adenosyl-L-methionine + erythromycin C | - |
Saccharopolyspora erythraea | S-adenosyl-L-homocysteine + erythromycin A | - |
? | |
2.1.1.254 | S-adenosyl-L-methionine + erythromycin D | - |
Saccharopolyspora erythraea | S-adenosyl-L-homocysteine + erythromycin B | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.1.254 | EryG | - |
Saccharopolyspora erythraea |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.1.1.254 | malfunction | eryG mutant strain lacks detectable erythromycin O-methyltransferase activity with erythromycin C, erythromycin D, or the analogs 2-norerythromycin C and 2-norerythromycin D as substrates | Saccharopolyspora erythraea |
2.1.1.254 | physiological function | the enzyme catalyzes all of the 3''-O-methylation reactions of the erythromycin biosynthetic pathway in Saccharopolyspora erythraea | Saccharopolyspora erythraea |